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Symbol
Name
ID
Ptpn22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
MGI:107170
Phenotype annotations related to renal/urinary system
Darker colors indicate more annotations
Human Phenotypes
Hematuria
Pyuria
Decreased level of D-mannose in urine
Proteinuria
Abnormality of the kidney
Lupus nephritis
Tubulointerstitial nephritis
Abnormal renal physiology
Polyuria
Nephritis
Renal insufficiency
Disease(s) Associated with PTPN22
Behcet's disease
Sjogren's syndrome
systemic lupus erythematosus
temporal arteritis
type 1 diabetes mellitus

Mouse Phenotypes
glomerulonephritis
expanded mesangial matrix
Availability Mouse Genotype
Ptpn22tm1.1Draw/Ptpn22tm1.1Draw
Gt(ROSA)26Sortm1(Ptpn22*)Draw/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory